ANTIMICROBIAL AND PHYTOCHEMICAL EVALUATION OF CISSUS QUADRANGULARIS L.

*Biresh Kumar Sarkar; Ravi Kumar; Vikas Kumar; Reeta Dr; Shashi Pal; C. Murali Krishna; S. C. Verma; Ravindra Singh; Ramaiah Maddi

*Biresh Kumar Sarkar Assistant Director, Central Ayurveda Research Institute for Respiratory Disorder, (CCRAS, Ministry of AYUSH, Govt. of India) Motibag Road, Patiala, Punjab, India.
Ravi Kumar Lab Technician, Central Ayurveda Research Institute for Respiratory Disorder, (CCRAS, Ministry of AYUSH, Govt. of India) Motibag Road, Patiala, Punjab,
Vikas Kumar JRF, Central Ayurveda Research Institute for Respiratory Disorder, (CCRAS, Ministry of AYUSH, Govt. of India) Motibag Road, Patiala, Punjab
Reeta Dr JRF, Central Ayurveda Research Institute for Respiratory Disorder, (CCRAS, Ministry of AYUSH, Govt. of India) Motibag Road, Patiala, Punjab
Shashi Pal Assistant Professor, Manav Bharati University, Solan, HP
C. Murali Krishna Regional Ayurveda Research Institute for Skin Disorders, (CCRAS, Ministry of AYUSH, Govt. of India), Vijayawada
S. C. Verma Pharmacopoeial Laboratory for Indian Medicine (PLIM) Ghaziabad, UP
Ravindra Singh Central Council for Research in Ayurvedic Sciences (CCRAS Ministry of AYUSH, Govt. of India), New Delhi
Ramaiah Maddi Dept. of Pharmacognosy, Hindu College of Pharmacy, Amaravathi Road, Guntur, A.P.

Keywords: Cissus quadrangularis, Herbs, Antimicrobial, HPTLC.

Abstract

The present investigation involves antimicrobial and phytochemical evaluation of Cissus quadrangularis L. The antibacterial activity of Cissus quadrangularis was performed using disk diffusion method. The Results of study proved prompt efficacy of herbal extract against S. aureus and E. coli. The concentration dependent antibacterial activity of extract was observed against both organisms. Study also involves phytochemical investigation of herbal extract using HPTLC, IR and UV-Visible spectrophotometer. The result of study indicated that the methanolic extract possessed most potent antibacterial activity as compared to other extract. The antibacterial activity increases with the concentration and results indicated that the diameters of zone inhibition of the extract were comparable with the standard drug. The antimicrobial potential of plant extract may be attributed to the presence of specific phytoconstituents.